Rehab Cell

Physical Medicine and Rehabilitation

Proteinuria: what is it, and what causes it?

Proteinuria: what is it, and what causes it?


Proteinuria is what is detected when we dip
your urine when you come to your GP perhaps for a medical or you go to an insurance company
and they look worried and tell you’ve got protein in your urine. What we need to do
then is quantify it and we can send off a urine sample to do that.
The reason you get protein in your urine, there are many causes, but fundamentally,
we all have protein in our blood. Things like albumin, and antibodies that we all make contribute
to protein in the blood and the kidneys filter huge amounts of blood every day but keep all
the protein in the blood, not in the urine. When the kidney is damaged for any reason,
if there’s inflammation, and there’s damage to what’s called the basement membrane which
is in the tiny capillaries in the glomeruli in the kidneys, then protein can leak out
when the blood is filtered, and that’s what you detect in a urine dip and are told you
have proteinuria. It indicates there’s a problem in the kidneys.
You might need a kidney biopsy to diagnose what that problem is and we’ll continue
to monitor the amount of protein and hope that it is reduced by our treatment whether
that’s controlling your blood pressure or your diabetes or treating another cause of
your kidney problems.

6 thoughts on “Proteinuria: what is it, and what causes it?

  1. i just had my urine test today and it says trace (only) in protein.my PUS cells is 1 to 3 and rbc is 0 to 1.my creatinine is 114 and the normal value is 63 to 107 mmol/l.is it ok?im scared 😢

  2. I have the problem as well. I guess once the damage is done there isn’t anything we can do to improve or solve this. Unfortunately there are so many potential causes it becomes a minefield trying to identify what caused the issue in the first place.

    I have been prescribed ramopril by my doctor and I guess there isn’t anything else I can do at this stage. The issue is the inflammation being caused and good luck finding out what is causing that. It could literally be anything.

    I just hope it doesn’t progress further into full on nephrotic syndrome. People die from that. Once your kidneys have gone, you’re pretty much finished

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